ElderD [@CaptainXtra](/forums/dis/topics/the-nerd-out-thread?post_id=5601694#post_5601694)
Modern cruisers and destroyers are very similar primarily because they use missles as their primary armament along with a single general purpose gun.
If you go to the first and Second World War however, there is a very notable difference in size and weaponry between them. Which kind of fits since most sci-fi ship battles use gun based combat.
Realistically, a space faring warship would be more like a submarine.