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safe2228364 applejack204915 fluttershy264821 pinkie pie261674 rainbow dash286310 rarity222280 twilight sparkle365694 earth pony528082 pegasus520471 pony1658436 unicorn563683 g42089626 artifact1828 caption26479 crazy face1299 cutie mark failure insanity syndrome9 derp8571 faic15094 flanderization77 flutterrage603 happy46212 image macro40388 impact font1951 insanity3456 mane six38298 meme95691 my little brony137 pinkamena diane pie22908 seasonal rot4 smiling418509 text93766 twilight snapple2384 twilighting440 unicorn twilight36036 watermark25184 you're going to love me273

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infinita est lux Solis
Artist -

Heretical Inquisitor
@Nashrakh
Hmm, if it were canon, would it merely be psychosomatic or a legit physiological condition… Like, it could be that the reason ponies go insane when they can’t fulfill their talents is because of how ponies are raised to take an immense amount of pride in their cutie marks to the point that I could see them going insane purely as a result of the societal pressures imposed upon them. but I can also see the cutie mark’s magic slowly ablating away at the pony’s mental state if they can’t live up to the talents dictated to them by their mark, therefore regardless of how the pony was raised they would still slowly go insane if prevented from doing what they’re magically gifted at.
Nashrakh

After all these years, I am still of the opinion that Cutie Mark Failure Insanity Syndrome is a real thing, and should be considered canon.