@D50  
This art does not make sense. They are not a couple.

@Millennial Dan
 
Yeah, the whole “Equestria Academy” thing turned out to be a mistranslation regarding the French title for the EQG subfranchise.

“Would you be willing to fill out a survey about your experiences with the supernatural?”

@Red Cedar  
That would be nice, but so far there’s no word of such a thing.

I’m guessing this is how the third and final Equestria Girls movie ends.
 
@Roy-of-Asturia  

 
You’re late. An EQG series is already in the works.

“But you’re not… ohhh. Oh oh ohhhhh. There’s two of you!” (devilish grin)

@Background Pony #97EE  
Simply put. Write letters or e-mail to Studio B and DHX (and TopDraw Animation) to conceive a 26-episode Equestria Girls cartoon. Enough to fill in the gaps and inconsistencies of Human!Equestria. I’ve readied my wishlists for that one, like the Mayor of Ponyville is suddenly the President of Human!Equestria.

@Background Pony #97EE
 
That’s a good way to put it, actually. Probably would be too complicated for the writing staff, though…

In all seriousness, I’m expecting the next EQG will be about Equestria Twilight more or less bowing out somehow, and Sci-Twilight taking over as that setting’s Twilight full-time. Sci-Twilight’s a good excuse to restart the premise of FiM, since she’s in pretty much the same state as Twilight was at the start of the series except with even fewer positive influences (no Celestia, a Spike that can’t talk).
 
That includes transferring Flash and Twilight’s relationship to Sci-Twilight. People have complained about Twilight and Flash having gotten together too quickly and without any real reason, but Sci-Twilight looks a lot colder and more resistant yet still has Twilight’s basic personality. It’d be easy to retell their relationship in long-form, where it takes much longer for Twilight to warm up to Flash but Flash has good cause to persevere knowing from his experiences with Equestria’s Twilight that deep down they’re a good match. It’s good fodder for a spinoff show if they go that route.
 
…Who knows? Maybe they’ll go full Reflections and Twilight will have to let Flash Sentry go because her crossing over into the human world (especially using her crazy science machine) is destabilizing the multiverse?

@Dirty Bit  
I don’t have a good follow up line, so I’m just going to post this.
 

@ZhaoZoharEX
 
“We go together like two pieces of recombinant DNA!”

“Let’s make science together.”
 
“…I’m afraid to ask in what way.”

I imagine Flash coming on to a completely oblivious Science Twilight and her reacting with pepper spray.

I don’t know how to feel about this XD
 
I’m thinking of Gravity Falls, where Bill Cipher possesses Dipper’s body.