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safe2241157 artist:bluse408 sci-twi32373 spike94327 spike the regular dog3274 twilight sparkle367607 dog14021 equestria girls264886 g42103012 my little pony equestria girls: rainbow rocks20333 adventure in the comments1351 angry37964 boots35610 clothes664976 collar50470 cute275945 doggy dragondox84 duality5691 feet56683 female1879455 glare9151 glasses93266 hallway1333 hand on hip14522 high heels18189 high res411596 hilarious in hindsight3893 lab coat3040 leash10957 legs12511 lockers2856 looking at each other37372 open mouth252224 sandals6200 self paradog10 self paradox4759 self ponidox10828 shirt43861 shoes63654 show accurate27788 signature48000 skirt58895 spikabetes3220 spike the dog3111 toes9980 twiabetes15959 twilight sparkle (alicorn)153477 twolight1636

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Background Pony #2F23
If the trailers (which, need I remind you, are just trailers) are of any indication then Science Twilight would be faced with a angry Twilight Prime (like Twilight’s Kingdom Part 2 angry).
Background Pony #E6E2
Human Twilight: I found you!
 
Twilight Prime: What do you want?
 
Human Twilight: Strange things are happening in this school and my readings point to myself as the culprit.
 
Twilight Prime: What’s going to happen to me now?
 
Human Twilight: We’re going to my lab… I have a present for you. Well it’s more like a medical procedure, actually it’s more like a medical experiment.