@Background Pony #73FA  
Which iteration of the Sinister Six had the Lizard in it?  
_{I’m mostly just familiar with the original line up.}

If you where to compare these with marvels sinister six, aria would be the lizard,

To be honest, the sirens look more like dragons then sea monsters.

Adagio is sunset shimmer right?

@SeraphimDawn  
Out of all the girls in the group, Suri comes in 3rd as the most meanest girl in the group; 2nd goes to Aria, and 1st goes to Adagio. Tho I do believe Suri might be a bit meaner than Aria, i’m pretty sure Aria would know how to put Suri in her place by letting her fists do all the talking for her, reminding Suri of how bad Coco Pommel must have felt when she was being mean to her.

I have to admit. As much of a #$%@ Suri Polomare is. She has cute design. Just unfortunate that she is one of the most unpleasant antagonists to appear on the show.

@Strawberry_Mask  
This was the best I could find on the internet. And in my opinion, non of them have a good fashion sence, except for Trixie. Her clothes matches her personality and EQG design best. And Dazzlings look a lot better when they’re all wearing their hoodies.

@SeraphimDawn  
Sombra could’ve been a big bad main villain with a legion of minions.

@Roy-of-Asturia  
I want to see them, the support character, and even Equestria face against a dynamic network and army of enemies and villains.
 
Whether it be an evil organization, cult, corporation, empire, or whatever. Make whoever is the opposing pony to Twilight a right hoof mare.

Since we’re tired of the Mane Six facing a single villain, you know it’s most likely either a mismatch or a handicap match.
 
Using this image above, alternate face-offs (Pony or Human):  
Twilight Sparkle v Trixie, again (Magic Duel version 2.0, except Trixie knows to use her street magic better)  
Pinkie Pie v Adagio Dazzle (Adagio must have taken the drifter / foreign exchange student Cheese Sandwich hostage)  
Applejack v Aria Blaze (THE most physically intense brawl ever)  
Fluttershy v Sonata Dusk (Choose your cutie pie or die)  
Lightning Dust v Rainbow Dash  
Suri Polomare v Rarity, again (P.S.: NO meta jokes. Hire a better English VA for Suri P. Sorry, critic here.)

@SeraphimDawn
 
Yeah, I was lost there for a moment. His suicide attempted failed, right? XD

Kind of an shame that suri and dust don’t have some more unique outfits

@Dirty Bit  
Funny how Dist is the only one left alive in the end.

@SeraphimDawn
 
I feel sorry for both of them. Sync was born a piece of meat and curses his very existence while making trouble for others. Meanwhile, Arietta’s getting shit from Anise despite her sad backstory.
 
The arc’s a good idea.

@Dirty Bit  
I think there should be a story arc where Equestria is face by an antagonist who invades Equestria with a large army, causing the Princesses to go exile for the duration of the season. The Empire then sends 6 elite generals or something, to each hunt down the Mane 6.

@Dirty Bit  
Sync isn’t afraid to die.  
The only one I can feel sorry for is Arrietta.

@SeraphimDawn
 
I like how each protagonist is connected with the six generals above them.
 
Well, except for Guy and Sync. Sync is badass…

The Six God Generals  

@Background Pony #BD73  
ever since the season 4 finale, i believe we can never trust anypony when they say they are on the “good side”
 
though i hope Dustie is good still no matter what (she will never be mentioned again i bet)

@RainbowDash69  
After what happened to Lightning Dust in Wonderbolt Academy, I doubt she’ll be a good girl next time she sees Rainbow Dash again. As for Trixie, if given a proper motivation, she could also go back to the dark side once more like the Dazzlings did, when they manipulated her into trapping the Rainbooms for them.
 
But this team up has more of a possibility of ever happening in the Equestria Girls universe, since Trixie has never been reformed in the human world yet, and the Dazzlings || might still want their revenge against the Rainbooms after what happened to them at the end of the movie.||

@Background Pony #BD73  
Good Argument! Thanks!!!

@Mega-Gojira  
They already did, Trixie lost. Applejack however, has been humiliated by Trixie twice in the past. Trixie might not want to fight her, but AJ might want to settle some scores with her.
 
Trixie is the opposite of Applejack, the way I see it. Applejack is well known for telling the truth, while Trixie is well known for telling lies. They both worked on farms, AJ likes working on her farm, while Trixie hated it but had to because she was poor. They both have their own giant mythical monster enemies, AJ’s are the Timberwolves and Trixie’s is the Ursa Minor. And they both have some competitive rivalry with Rainbow Dash.
 
Those are the reasons why Trixie is the Applejack of this group.

Sinister Six??? Spider Vibe!!!
 
Personally, I would have Trixie vs Twilight